Short-acting GHRH analog to stimulate natural GH pulses
Heather
Last Update vor 5 Monaten
Category:
Growth Hormone Support / Recovery / Anti-Aging
Primary Benefits:
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Stimulates natural GH pulsatile release
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Enhances lean muscle growth and fat loss
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Supports recovery, sleep, and collagen synthesis
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Best when paired with a GHRP (e.g., Ipamorelin)
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Mimics natural circadian rhythm of GH release
Mechanism of Action:
CJC-1295 (without DAC) is a modified growth hormone–releasing hormone (GHRH 1-29) that has a shorter half-life and mimics the body’s natural pulsatile GH release. It acts on the pituitary to release growth hormone in sync with the body’s natural rhythms. Because it lacks DAC, it avoids prolonged receptor saturation and is suited for daily use.
Dosing & Protocol:
Subcutaneous (SQ) Injection:
• Reconstitution:
2 mg vial → 2.0 ml bacteriostatic water (= 100 mcg per 10 units)
5 mg vial → 2.5 ml bacteriostatic water (= 200 mcg per 10 units)
• Daily Dose:
– 100–200 mcg
• Cycle:
5 days on, 2 days off
8–12 weeks on, followed by 2–4 weeks off
• Timing:
Administer 1x or 2x daily
Ideal: Morning and/or 1 hour before bedtime on an empty stomach
Potential Side Effects:
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Mild flushing or warmth post-injection
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Temporary headache or lightheadedness
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Tingling in hands/feet due to GH surge
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May reduce insulin sensitivity at very high doses
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Not advised for use near food or insulin
Common Stacks:
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With Ipamorelin: Creates synergistic GH pulse without desensitization
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With BPC-157 or TB-500: For enhanced recovery from training or injury
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With CJC-1295 with DAC (cycled): Long + short GH modulation
Notes:
CJC-1295 without DAC should be taken on an empty stomach and spaced away from meals or insulin to prevent interference with GH release. Best results occur when combined with a GHRP like Ipamorelin. Store reconstituted vial in the refrigerator and discard after 30–45 days.
Disclaimer:
The information provided in this article is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the FDA or Health Canada. Peptides and other compounds discussed are intended for research purposes only and are not approved for human consumption unless prescribed by a licensed medical professional. Always consult your healthcare provider before starting any new protocol, supplement, or treatment.